At what level should you begin the administration of nitrous oxide?

Beginning the administration of nitrous oxide at a concentration of 10% is a standard practice because it often provides the optimal balance between achieving anxiolysis and maintaining patient comfort without excessive sedation. Starting at this level allows for gradual titration, enabling practitioners to assess the patient's response before increasing the concentration if needed. Nitrous oxide is a relatively safe agent, and beginning at a moderate level helps in minimizing potential side effects while allowing the clinician to gauge the patient’s tolerance and effectiveness of the sedation.

In clinical practices, administering nitrous oxide at too low a concentration may not yield adequate anxiolytic effects, while starting at higher concentrations could lead to discomfort or undesirable sedation levels. Therefore, 10% serves as a well-recommended starting point for effective and safe nitrous oxide administration.